Features |
NanoDrop One / One C |
Implen NanoPhotometer® N60/NP80 |
Instrument Performance |
Minimum Sample Volume |
1 µL
2 µl sample size is recommended for protein measurements |
 0.3 – 2 μL |
Pathlength |
0.03 – 1 mm
Auto-ranging
Recalibration recommended by manufacturer
|
 Utilizes two fixed path lengths 0.67 and 0.07 mm
Fixed path lengths never change over the lifetime of the instrument |
Measurement Time |
8 seconds
|
 2.5 – 4 seconds
(full scan 200 – 900 nm) |
Enclosed Sample Measurement Surfaces |
NO
Column is exposed to surroundings, leading to sample evaporation. |
 YES
Enclosed sample measurement surfaces
No evaporation
Accurate results independent from environmental conditions
Ability to measure proteins with detergent buffers without sample build-up |
Photometric Range Cuvette |
0 – 1.5 A |

0 – 2.6 A |
Organic Solvents |
N/A |

Enabled |
Detection Range* |
dsDNA: 2 – 27,500 ng/µl
BSA: 0.06 – 820 mg/ml |

dsDNA: 1 – 16,500 ng/µl
BSA: 0.03 – 478 mg/ml |
Optical Specifications |
Measurement Wavelength |
Full scan from 190 – 850 nm |

Full scan from 200 – 900 nm |
Illuminated Read Head |
N/A |
 Illuminated read head for an easy sample application |
Light Source |
Xenon Flash Lamp |
 Xenon Flash Lamp |
Instrument Features |
Maintenance-free |
NO
Thermo Fisher Scientific recommends performing a Calibration Check using CF-1 calibration check fluid every 6 months and regular service every year |
 YES
No recalibration
No reconditioning
Maintenance-free over the entire lifetime |
Reconditioning-free |
NO
The pedestal of the instrument may become unconditioned over time, especially when measuring proteins or samples that contain surfactants or detergents. This requires reconditioning of the unit’s pedestal. |
 YES
Scratch-resistant inert quartz pedestal that requires no reconditioning |
Quality Control Warnings |
Acclaro Technology with contaminate calculations |
 Sample Control™: quality control technology identifies sample impurities, potential contaminants, turbidity and lint residue
Blank Control™: prevents inaccurate readings caused by high background blanks or insufficient cleaning |
Built-in Web Application Server |
NO
Limited Android-based internal computer only
|

Full Web Application Server with REST API |
21 CFR part 11 |
By external computer only
|

Stand-alone and by external computer |
Processing Power, Compatibility, Data Processing |
Operating System |
Android |

Linux based NPOS (NanoPhotometer Operating System) Open platform to connect to Windows, Mac OS, Android, iOS via web application interface |
Onboard Processor |
Quad Core
ARM Cortex
A9 Processor |
 Built-in computer with high-performance Intel Celeron dual core 2.4 GHz processor |
Internal Data Storage |
32 GB |
32 GB for storage of thousands of measurements |
Software Compatibility |
Compatible with Windows only |

Compatible with Windows 7, 8, 10 (32 and 64 bit), Mac OS X, iOS and Android OS
|
Data Transfer and Connectivity Options |
The unit includes 3x USB A, Ethernet, Bluetooth, WiFi |
 The unit includes 2x USB A, USB B, HDMI, Ethernet, WiFi |
Data Output |
Separate as .csv .tsv .sql |
 Complete data as PDF & Excel |
Instrument Control |
The device can be connected to a computer via USB cable for operation, control and data storage.
|

Easy control of the NanoPhotometer is possible via Wi-Fi from tablets or smartphones (Android OS & iOS). Control from PCs via LAN, WiFi or USB (Windows & Mac). The HDMI port allows for presentations directly from the device. |
WiFi Hotspot |
Client possible |

Built-in WiFi hotspot and with WiFi client capability |
Instrument Dimensions |
20 × 25.4 × 32.3 cm
(8 × 10 × 12.7 inches) |
20 x 20 x 12 cm
(7.9 x 7.9 x 4.7 inches) |