NanoPhotometer® N60/N50


Nucleic Acid & Protein UV-Assay Measurements, plus much more | Starting at 0.3 µl | Scan Range 200 – 900 nm


Broad Detection Range*
dsDNA: 1 – 16,500 ng/µl  |  BSA: 0.03 – 478 mg/ml

Built-in Vortex* Low vibration and low energy vortex
Standalone or Remote Operated Windows, Mac, Android, and iOS
Portable with Battery Option Only 20 x 20 x 12 cm footprint
5-Star Customer Support Live, application support 24/5
GMP, GLP, GxP Ready 21 CFR Part 11 and IQOQ option*


Saves time and avoids manual dilution errors
Improved sample homogeneity for more accurate readings
Flexible unit control and access to data from anywhere
Ready to go into a glove box, under the hood, from lab bench to lab bench, or into the field
Expert knowledge when you need it
Full laboratory compliance with a peace of mind

*NanoPhotometer® N60 only | **Detection range for N50: dsDNA: 5 – 7,500 ng/µl BSA: 0.15 – 217 mg/ml


Preprogrammed Applications & Features

  • Nucleic Acids (DNA, RNA, mRNA, Oligos, etc.) with QC Ratios (260/280 and 260/230)
  • Protein UV with QC Ratio (260/280)
  • Measure fluorescent dye-labeled Nucleic Acids and Proteins using absorbance
  • Potential contaminant identification
  • Further Life Science applications: OD600, Protein Assays (Bradford, BCA, Biuret), Kinetics in a drop
  • UV-Vis Spectroscopy applications: Wavelength (including formula editor), Wavescan, Standard Curve, Concentration, Absorbance Ratio

Best-in-class MicroVolume Spectrophotometer

Best in class microvolume spectroscopy with the convenience of a lightweight portable UV/Vis spectrophotometer mainly for nucleic acid quantification and protein quantitation and many other UV/Vis spectroscopy methods with a built-in 7 inch LCD glove compatible touchscreen with flexible unit control options. Built-in vortex provides sample uniformity of homogenous samples for the highest degree of accuracy with the smallest sample volume with as little as 0.3 µl. Illuminated quartz sample surface allows for an easy sample application.
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Mobile Design

Microvolume spectroscopy can now be taken anywhere in the small light-weight size UV/Vis spectrophotometer of 20x20x12 cm and between 3.8 to 5 kg depending on the configuration. Mobility is redefined with an optional built-in battery pack for up to 8 hours of stand-alone operation.

Battery pack option not available for N50 model

Stand-Alone Operation

No computer required. Built-in Computer with high performance Intel Celeron dual-core 2.4 GHz processor and 32 GB of onboard memory provide powerful and easy storage of methods and data. Preprogrammed UV/Vis spectrophotometer applications are available for nucleic acid quantitation and purity check using the 260/280 and 260/230 ratio (dsDNA, ssDNA, RNA, mRNA, miRNA, Oligos including dye-labeled samples) as well as for protein quantitation and purity check using the 260/280 ratio (BSA, Antibodies, IgG, IgE, Serum Albumin, etc., including dye-labeled samples), small molecules in organic solvents, kinetics, and more.
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Accurate Spectroscopy

Sample Compression Technology™ provides unmatched precision and accuracy with reliable UV/Vis spectrophotometer measurement geometry of challenging samples including proteins. A capillary film is formed between two quartz surfaces with each sample eliminating the need for surface tension and avoiding evaporation. This guarantees accurate and reliable readings for Nucleic Acid and Protein quantifications as well as purity checks for 260/280 and 260/230 ratios and other UV/Vis spectroscopy applications including kinetics in a drop.

Built-in Vortex

Achieve sample uniformity by vortexing prior to each measurement with the proprietary built-in NanoPhotometer® low vibration / low energy vortexer for a gentle homogenizing of even delicate samples; obtain readings that represent the accurate concentration of the entire sample.

Certainty in Real Time

Sample Control™ – the leading edge quality control technology for UV/Vis spectrophotometers to identify air bubbles, sample impurities, turbidity, lint residue and potential contaminations also utilizing 260/280 and 260/230 ration calculations and determinations. Sample Control™ monitors handling characteristics and sample quality in real time to ensure that the measured concentrations of e.g. nucleic acids and proteins are reproducible and most precise.

Endless Connectivity

Equipped with Wi-Fi, built-In HotSpot, LAN, HDMI and USB A/B interface connections for remote instrument control, data accessibility and printing. NPOS now supports AirPrint /IPP compatible printers supporting PDF format, printers compatible with the HP universal driver and DYMO label printers (cryo and standard labels). The NanoPhotometer® is compatible with 1 and 2D bar code readers allowing for flexible and streamlined data entry. Unique file server functionality allows access of data stored on the NanoPhotometer® drive from any computer accessing the lab network.
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Universal Data Output

Every NanoPhotometer® is able to generate formatted Excel and PDF document files for data processing or archiving of measurements on the lab network. The capability to print full page reports, labels and cryo labels via USB and through a network connection lends users the upmost flexibility for data output. Supported printers include AirPrint/IPP compatible printers supporting PDF format, printers with HP universal printer driver capability and DYMO label printers.
AirPrint® is a registered trademark of Apple Inc. Cupertino, CA

Flexible Unit Control

Mobile and easy control of the NanoPhotometer® is possible via Wi-Fi from tablets or smartphones (Android OS & iOS). Easy control from PCs (Windows & Mac) with fast and flexible connection options including Wi-Fi, USB and LAN.
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Ultimate Data Security

Malware, viruses and ransomware are serious threats to instrumentation working on Android or Windows based platforms. The proprietary NanoPhotometer® Operating System NPOS protects data in a secure environment immune to known malicious software. Whether running Apps on the NanoPhotometer/control device or downloading precious measurement results, your data is safe. For additional security the NanoPhotometer® does not allow browsing on the internet whilst providing safe access to control devices like computers, tablets and smart phones.

CFR21 Software

The CFR21 software complies with FDA 21 CFR Part 11 requirements and is an optional software tool ideal for GxP laboratories, which require proper electronic record-keeping for UV/Vis spectroscopic measurements utilizing a microvolume or cuvette UV/Vs spectrophotometer. It includes user management, access control, electronic signatures, data integrity, security, and audit trail functionality.
Not available for the NanoPhotometer® N50.
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Fast & Maintenance Free Spectrophotometer

Turn on and instantly measure without lamp warm up time. Full scan capability range from 200-900 nm (N50: 200-650 nm) for rapid and complete sample analysis in as little as 2.5 seconds (N50: 6.0sec). True Path Technology™ covers the extensive dynamic range with two precisely defined path lengths. The sealed mechanical setup has two fixed anchor points that are not changing over the lifetime of the instrument. No recalibration is necessary, Implen guarantees lifetime accuracy.

Confidence with Blank Control™

Be sure that your data are precise with Implen’s unique Blank Control™ feature for UV/Vis spectrophotometers. Blanks with high background or residues from previous users are the main cause of inaccurate readings. Blank Control™ will protect you from wasting time and precious samples (e.g. nucleic acid and/or protein samples) on inaccurate readings caused by high background blanks or inappropriate cleaning.
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Universal Linguist

NPOS now offers the user interface in a selection of languages. The advanced language functionality allows the operator to effectively understand and interact with the unit, boosting productivity in the lab. In addition to a new multilingual user interface, the NanoPhotometer® provides the flexibility to print results in multiple languages, which prevents misinterpretation of data and time consuming translations. The selection covers most widely spoken languages including English, Chinese, French, German, Japanese, Portuguese, Russian, and Spanish and will be continuously extended.

Fun for committed Spectroscopy Nerds: the NanoPhotometer® Crew

Meet the most dedicated individuals and witness their selfless never-ending commitment to provide trustworthy UV/Vis spectrophotometer results for researchers in every country around the world. Their adventures to provide highly accurate nucleic acid and protein quantification readings, purity checks (260/280 and 260/230 ratios) and other UV//Vis spectroscopy applications have been videotaped and are available on every instrument starting with firmware version 4.3 installed – with the new screensaver feature activated.

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